From I-275 N, Use The Right 2 Lanes To Take Exit 45B For I-4 E Toward Orlando. Continue Onto I-4 E. Take Exit 1 Toward Cruise Ships/21St St/22Nd Street. Merge Onto E 13Th Ave/Ybor Frontage Rd S. Turn Left Onto Fl-585 N/N 22Nd Street. Turn Left Onto E 17Th Ave. Turn Left At The 1St Cross Street Onto Fl-585 S/N 21St Street And The Destination Will Be On The Left.