Directions From Downtown Tampa To 3421 E Powhatan Ave: Start In Downtown Tampa And Head East On E Kennedy Blvd Toward N Morgan St. Turn Left Onto N Nebraska Ave. Continue Straight For About 2 Miles. Turn Right Onto E Dr Martin Luther King Jr Blvd (Mlk Blvd). After About 0.5 Miles, Turn Left Onto N 34Th St. Go Straight For 0.3 Miles, Then Turn Right Onto E Powhatan Ave. The Destination, 3421 E Powhatan Ave, Will Be On Your Left. Travel Time: Approximately 10-15 Minutes, Depending On Traffic.